A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila

摘要

An analysis of dendritic and axonal phenotypes of kinesin heavy chain (KHC) loss-of-function clones revealed a role for KHC in maintaining polarity of neurons, as well as ensuring proper axonal outgrowth. Adenomatous polyposis coli 1 was identified as an interaction partner of KHC to control directed transport and modulate kinesin function in neurons.